Sertraline is a medication that belongs to a group of antidepressants referred to as selective serotonin reuptake inhibitors (SSRIs). And treating depression, the may aid people suffering premature ejaculation.

Premature ejaculation (PE) is a problem in i m sorry a human being with a prick ejaculates an extremely quickly when sexually stimulated. Sertraline may aid a human being last longer prior to ejaculating.

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In this article, we look at both sertraline and also PE in much more detail. We additionally discuss the efficiency of sertraline as a therapy for PE and also list some alternate treatment options.

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Sertraline, also known through the brand surname Zoloft, is one antidepressant. It is an SSRI the can assist treat depression, anxiety, and some various other mood disorders.

Sertraline works by boosting the level of serotonin in the brain. Serotonin is a neurotransmitter the transmits messages in between neurons.

As well as regulating mood, serotonin also plays a duty in memory, eating, and sleep.

PE is a fairly common problem in which a human being ejaculates easily with very little sexual stimulation. It have the right to be frustrating for the individual and can often lead to unfulfilling sex-related interactions.

PE can happen as a result of mental or physical factors or a mix of both. Some of these may include:

prostate difficulties thyroid conditionsuse of to chat drugsdepression relationship problemsanxiety around sex and sexual performanceconditioned behaviors, such together ejaculating easily from masturbationtraumatic sexual experiencesstrict upbringing and beliefs around sex
Effectiveness because that PE

There is some scientific proof to imply that SSRIs may be an reliable treatment because that PE. Although that does not cite sertraline special, a 2019 study states that SSRIs room the gold standard of therapy for PE.

A systematic testimonial looking in ~ the efficacy and safety of sertraline for PE suggests that that can help prolong ejaculation and improve sex-related satisfaction for civilization with this condition and their partners.

A 2019 examine looked in ~ two teams of human being with PE. One group took sertraline double daily, while the other took it 4 hours prior to sex. The researchers uncovered that both everyday use that the drug and also taking the a couple of hours before sex increased ejaculation time.

Risks and side effects

People have to be aware that sertraline has actually a few possible next effects, including:

nauseatremordecreased appetitefailure to ejaculatedecreased sex drive

Once a human becomes accustomed to the medication, that is most likely that the side results will lessen. If the side impacts are persistent or extreme, a person should discuss stopping the medication v their doctor.

However, fairly than suddenly stopping the medication, a human should gradually reduce the dose to protect against extra side effects.

Learn much more about the side effects of sertraline.

How to use it

A human who wishes to take it sertraline for PE will need to gain a prescription indigenous their medical care provider.

Sertraline dosages deserve to vary. In the 2019 examine above, the participants in the an initial group obtained the medicine in a 50-milligram (mg) sheep every 12 hours. However, sertraline can come in dosages as low together 25 mg per day and also as high as 200 mg per day.

A physician will be able to advise a person on the ideal dosage that sertraline to assist with PE.


Although sertraline is one possible treatment for PE, there are several alternative treatments that a person may want to try. Few of these might be beneficial for addressing the underlying cause of PE.

Some examples of alternative treatments because that PE include:

Sex therapy

If the cause of PE is psychological, it might be useful for a human being to to visit sex therapy.

A sex therapist can assist counsel a human being to deal with any emotional worries or trauma the is leading to the condition. Castle can additionally suggest behavior techniques to increase the time that it take away a person to ejaculate.

Behavioral techniques

Behavioral techniques are exercises the a person deserve to practice to assist them delay their ejaculation.

A famous behavioral technique for PE is the stop-start technique, which requires a person (or their partner) stimulating the prick until they are near ejaculation. As soon as they notice this sensation, they protect against stimulating the penis and also let the sensation pass.

The human should repeat this process a couple of times before ejaculating.


If the cause of PE is a physical condition, such as an concern with the thyroid, a physician may provide oral medication to attend to the condition directly.

Desensitizing sprays

Desensitizing sprays work by applying a regional anesthetic to the head and shaft that the penis. The anesthetic numbs the area slightly, resulting in a less intense feeling throughout sexual activity and intercourse.

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An older study highlights that applying a specific PE spray 5 minutes before sex resulted in study participants having better control end ejaculation and an increase in sexual satisfaction.